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Arachnoid or Pacchionian granulations and MS lesions
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Author:  Jencor69 [ Mon, 24 Dec 2012, 3:42 pm ]
Post subject:  Arachnoid or Pacchionian granulations and MS lesions

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I remembered something that Dr Sclafani discovered during my CCSVI treatment earlier this year. It got me thinking in relation to Dr Amir's thoughts about MS lesions.

Dr Sclafani wrote, "Right dural sinus and right internal jugular venography revealed that there was a filling defect in the transverse sinus. Intravascular ultrasound showed an appearance that was strongly suggestive of a prominent Pacchionian granulation."

According to Wikipedia, The arachnoid granulations act as one-way valves. Normally the pressure of the CSF is higher than that of the venous system, so CSF flows through the villi and granulations into the blood. If the pressure is reversed for some reason, fluid will not pass back into the subarachnoid space (of the brain). The reason for this is not known. It has been suggested that the endothelial cells of the venous sinus create vacuoles of CSF, which move through the cell and out into the blood.

Occasionally, they are referred to by their old name: Pacchioni's granulations or pacchionian bodies, named after Italian anatomist Antonio Pacchioni.

http://en.wikipedia.org/wiki/Arachnoid_granulation

They are considered to have no clinical significance but I still find it interesting that they function as one-way valves, like pressure valves for cerebrospinal fluid. The other interesting thing is the fact that larger granulations can mimic lesions on MR scans. The MS lesions on my MRI scans may not be lesions after all?

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